COVID-19 severity and outcome in multiple sclerosis: Results of a national, registry-based, matched cohort study.

ABSTRACT:

Background

Risk factors associated with coronavirus disease 2019 (COVID-19) severity in patients with multiple sclerosis (MS) have been described. Recent improvements in supportive care measures and increased testing capacity may modify the risk of severe COVID-19 outcome in MS patients. This retrospective study evaluates the severity and outcome of COVID-19 in MS and characterizes temporal trends over the course of the pandemic in the United States.

Methods

We conducted a comparative cohort study using de-identified electronic health record (EHR) claims-based data. MS patients diagnosed with COVID-19 between February 2, 2020 and October 13, 2020 were matched (1:2) to a control group using propensity score analysis. The primary outcome was a composite of intensive care unit

SUBMITTER: Perez CA 

PROVIDER: S-EPMC8366056 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature