Cardiac risk stratification in cancer patients: A longitudinal patient-patient network analysis.

ABSTRACT:

Background

Cardiovascular disease is a leading cause of death in general population and the second leading cause of mortality and morbidity in cancer survivors after recurrent malignancy in the United States. The growing awareness of cancer therapy-related cardiac dysfunction (CTRCD) has led to an emerging field of cardio-oncology; yet, there is limited knowledge on how to predict which patients will experience adverse cardiac outcomes. We aimed to perform unbiased cardiac risk stratification for cancer patients using our large-scale, institutional electronic medical records.

Methods and findings

We built a large longitudinal (up to 22 years' follow-up from March 1997 to January 2019) cardio-oncology cohort having 4,632 cancer patients in Cleveland Clinic with 5 diagnosed ca

SUBMITTER: Hou Y 

PROVIDER: S-EPMC8366997 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature