Amyloidosis with Cardiac Involvement: Identification, Characterization, and Management.

ABSTRACT:

Purpose of review

Amyloidosis is a protein deposition disease whereby a variety of precursor proteins form insoluble fibrils that deposit in tissues, causing organ dysfunction and, many times, death. Accurate characterization of the disease based on the nature of the precursor protein, organ involvement, and extent of disease is paramount to guide management. Cardiac amyloidosis is critical to understand because of its impact on prognosis and new treatment options available.

Recent findings

New imaging methods have proven to be considerably valuable in the identification of cardiac amyloid infiltration. For treating clinicians, a diagnostic algorithm for patients with suspected amyloidosis with or without cardiomyopathy is shown to help classify disease and to direct appropr

SUBMITTER: Jamal F 

PROVIDER: S-EPMC8367912 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature