Local anisotropy in mineralized fibrocartilage and subchondral bone beneath the tendon-bone interface.

ABSTRACT: The enthesis allows the insertion of tendon into bone thanks to several remarkable strategies. This complex and clinically relevant location often features a thin layer of fibrocartilage sandwiched between tendon and bone to cope with a highly heterogeneous mechanical environment. The main purpose of this study was to investigate whether mineralized fibrocartilage and bone close to the enthesis show distinctive three-dimensional microstructural features, possibly to enable load transfer from tendon to bone. As a model, the Achilles tendon-calcaneus bone system of adult rats was investigated with histology, backscattered electron imaging and micro-computed tomography. The microstructural porosity of bone and mineralized fibrocartilage in different locations including enthesis fibrocartilage

SUBMITTER: Tits A 

PROVIDER: S-EPMC8367976 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature