Chorioretinal paracoccidioidomycosis treated with intravitreal voriconazole and therapeutic vitrectomy.

ABSTRACT:

Purpose

To report a case of aggressive chorioretinal paracoccidioidomycosis requiring treatment with systemic antifungal agents, frequent intravitreal voriconazole injections, and surgical excision.

Observations

A Brazilian man in his mid-30s with a history of chronic, biopsy-proven cutaneous paracoccidioidomycosis, chronic sinusitis, and perichondritis secondary to paracoccidioidomycosis presented with profound vision loss. He was found to have significant vitreous inflammation and a large chorioretinal lesion in the posterior pole concerning for ocular involvement. He was treated initially with combined topical and systemic steroids as well as systemic antifungals and antibiotics, then with serial intravitreal voriconazole injections resulting in a significant reduction of

SUBMITTER: Oke I 

PROVIDER: S-EPMC8368784 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature