Diffusion-prepared fast spin echo for artifact-free spinal cord imaging.

ABSTRACT:

Purpose

Diffusion MRI provides unique contrast important for the detection and examination of pathophysiology after acute neurologic insults, including spinal cord injury. Diffusion weighted imaging of the rodent spinal cord has typically been evaluated with axial EPI readout. However, Diffusion weighted imaging is prone to motion artifacts, whereas EPI is prone to susceptibility artifacts. In the context of acute spinal cord injury, diffusion filtering has previously been shown to improve detection of injury by minimizing the confounding effects of edema. We propose a diffusion-preparation module combined with a rapid acquisition with relaxation enhancement readout to minimize artifacts for sagittal imaging.

Methods

Sprague-Dawley rats with cervical contusion spinal cord in

SUBMITTER: Lee SY 

PROVIDER: S-EPMC8369385 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature