Exposure to aflatoxins and fumonisins and linear growth of children in rural Ethiopia: a longitudinal study.

ABSTRACT:

Objective

We hypothesise that exposure to aflatoxins and fumonisins, measured in serum, alters protein synthesis, reducing serum protein and insulin-like growth factor 1 (IGF-1), increasing inflammation and infection, leading to child's linear growth failure.

Design

Children 6-35 months, stratified by baseline stunting, were subsampled from an intervention trial on quality protein maize consumption and evaluated at two time-points.

Setting

Blood samples and anthropometric data were collected in the pre-harvest (August-September 2015) and post-harvest (February 2016) seasons in rural Ethiopia.

Participants

102 children (50 stunted and 52 non-stunted).

Results

Proportions of children exposed to aflatoxin G1, aflatoxin G2 and aflatoxin M1 were higher in the

SUBMITTER: Tessema M 

PROVIDER: S-EPMC8369457 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature