Anticancer bispecific antibody R&D advances: a study focusing on research trend worldwide and in China.

ABSTRACT:

Background

The bispecific antibody (bsAbs) research around the world has undergone great changes. We analyzed the global trend of bsAbs research and compared the differences in clinical research of bsAbs between China and worldwide.

Methods

BsAbs research clinical trials information was retrieved through the online open-resource clinical trial registration platform. Research information including organizations, identity numbers, locations, phases, participating centers, conditions, status, enrollment, targets, spectrums of mechanism of action (MOA), and start date was collected. Clinical trials were divided into two categories based on the attributes of pharmaceutical companies (international or China-initiated or involved).

Results

From 1997 to 2020, 272 clinical tri

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC8369643 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature