Longitudinal changes in the inferior cerebellar peduncle and lower limb motor recovery following subcortical infarction.

ABSTRACT:

Background

The cerebellum receives afferent signals from spinocerebellar pathways regulating lower limb movements. However, the longitudinal changes in the spinocerebellar pathway in the early stage of unilateral supratentorial stroke and their potential clinical significance have received little attention.

Methods

Diffusion tensor imaging and Fugl-Meyer assessment of lower limb were performed 1, 4, and 12 weeks after onset in 33 patients with acute subcortical infarction involving the supratentorial areas, and in 33 healthy subjects. We evaluated group differences in diffusion metrics in the bilateral inferior cerebellar peduncle (ICP) and analyzed the correlation between ICP diffusion metrics and changes to the Fugl-Meyer scores of the affected lower limb within 12 weeks a

SUBMITTER: Liu G 

PROVIDER: S-EPMC8369783 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature