Efficaciousness of dexmedetomidine in children undergoing cleft lip and palate repair: a systematic review and meta-analysis.

ABSTRACT:

Objective

To systematically assess the efficacy and safety of dexmedetomidine as an anaesthesia adjuvant for cleft lip and palate (CLP) repair in children.

Design

Systematic review and meta-analysis.

Data sources

PubMed, Embase, Cochrane, China National Knowledge Infrastructure (CNKI), China Science and Technology Journal Database (VIP) and Wanfang (up to October 2020). Studies in languages other than English and Chinese were excluded.

Eligibility criteria for selecting studies

Randomised controlled trials (RCTs) evaluating the impact of dexmedetomidine on emergence agitation (EA), the need for postoperative rescue analgesics, postoperative nausea and vomiting (PONV), and other adverse events in paediatric patients during CLP repair.

Data extraction and synt

SUBMITTER: Liu D 

PROVIDER: S-EPMC8370512 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature