Detailed Episodic Memory Depends on Concurrent Reactivation of Basic Visual Features within the Posterior Hippocampus and Early Visual Cortex.

ABSTRACT: The hippocampus is a key brain region for the storage and retrieval of episodic memories, but how it performs this function is unresolved. Leading theories posit that the hippocampus stores a sparse representation, or "index," of the pattern of neocortical activity that occurred during perception. During retrieval, reactivation of the index by a partial cue facilitates the reactivation of the associated neocortical pattern. Therefore, episodic retrieval requires joint reactivation of the hippocampal index and the associated neocortical networks. To test this theory, we examine the relation between performance on a recognition memory task requiring retrieval of image-specific visual details and feature-specific reactivation within the hippocampus and neocortex. We show that trial-by-trial r

SUBMITTER: Bone MB 

PROVIDER: S-EPMC8370760 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature