A tailored approach in lymph node-positive perihilar cholangiocarcinoma.

ABSTRACT:

Purpose

Extended right hepatectomy is associated with wide surgical margins in PHC and often favored for oncological considerations. However, it remains uncertain whether established surgical principles also apply to the subgroup of node-positive patients. The aim of the present study was to define a tailored surgical approach for patients with perihilar cholangiocarcinoma (PHC) and lymph node metastases.

Methods

We reviewed the course of all consecutive patients undergoing major hepatectomy for PHC between 2005 and 2015 at the Department of Surgery, Charité - Universitätsmedizin Berlin.

Results

Two hundred and thirty-one patients underwent major hepatectomy for PHC with 1-, 3-, and 5-year overall (OS) and disease-free survival (DFS) rates of 72%, 48%, and 36%, and 60

SUBMITTER: Benzing C 

PROVIDER: S-EPMC8370897 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature