Multicenter prospective in vivo study of an endocytoscope system (ECS) for superficial esophageal cancer.

ABSTRACT:

Background

Endocytoscope systems (ECS) can visualize cellular nuclei of the mucosa of the gastrointestinal tract and are predicted to provide real-time microscopic diagnosis. However, their practical diagnostic performance remains unclear. Therefore, we conducted a multicenter prospective study to evaluate the visualization of superficial esophageal neoplasm in vivo using an ECS, and its diagnostic capability.

Methods

The study target was histologically confirmed squamous cell carcinoma (SCC) and high-grade intraepithelial neoplasia (HGIN). An integrated ECS was used to obtain ECS images. In each patient, three ECS images of cancerous and corresponding noncancerous regions were selected for evaluation. A pathological review board of five certified pathologists made the final

SUBMITTER: Morita S 

PROVIDER: S-EPMC8370913 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature