Clinical features of patients with HER2-positive breast cancer and development of a nomogram for predicting survival.

ABSTRACT:

Background

Different estrogen receptor (ER) and progesterone receptor (PR) expression patterns have important biological and therapeutic implications in patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer. However, little is known about hormone receptor (HR)-positive and triple-positive subtypes, making therapy selection and survival prognosis difficult. This study investigated the clinical characteristics and nomogram-predicted survival of patients with HER2-positive breast cancer.

Materials and methods

Data on patients with HER2-positive breast cancer were retrieved from the Surveillance, Epidemiology, and End Results database. Comparisons were carried out between single HR-positive and double HR-positive/double HR-negative subtypes. A nomo

SUBMITTER: Fan Y 

PROVIDER: S-EPMC8371219 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature