Relationships between apparent cortical thickness and working memory across the lifespan - Effects of genetics and socioeconomic status.

ABSTRACT: Working memory (WM) supports several higher-level cognitive abilities, yet we know less about factors associated with development and decline in WM compared to other cognitive processes. Here, we investigated lifespan changes in WM capacity and their structural brain correlates, using a longitudinal sample including 2358 magnetic resonance imaging (MRI) scans and WM scores from 1656 participants (4.4-86.4 years, mean follow-up interval 4.3 years). 8764 participants (9.0-10.9 years) with MRI, WM scores and genetic information from the Adolescent Brain Cognitive Development study were used for follow-up analyses. Results showed that both the information manipulation component and the storage component of WM improved during childhood and adolescence, but the age-decline could be fully explain

SUBMITTER: Krogsrud SK 

PROVIDER: S-EPMC8371229 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature