Associations of BNT162b2 vaccination with SARS-CoV-2 infection and hospital admission and death with covid-19 in nursing homes and healthcare workers in Catalonia: prospective cohort study.

ABSTRACT:

Objective

To determine associations of BNT162b2 vaccination with SARS-CoV-2 infection and hospital admission and death with covid-19 among nursing home residents, nursing home staff, and healthcare workers.

Design

Prospective cohort study.

Setting

Nursing homes and linked electronic medical record, test, and mortality data in Catalonia on 27 December 2020.

Participants

28 456 nursing home residents, 26 170 nursing home staff, and 61 791 healthcare workers.

Main outcome measures

Participants were followed until the earliest outcome (confirmed SARS-CoV-2 infection, hospital admission or death with covid-19) or 26 May 2021. Vaccination status was introduced as a time varying exposure, with a 14 day run-in after the first dose. Mixed effects Cox models were

SUBMITTER: Cabezas C 

PROVIDER: S-EPMC8371258 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature