Outcome Squares Integrating Efficacy and Safety, as Applied to Functioning Pituitary Adenoma Surgery.

ABSTRACT:

Context

Transsphenoidal surgery is standard care in the treatment of hormone-secreting pituitary adenomas. Current clinician-reported surgical outcome measures are one-dimensional, typically focusing primarily on complete or partial resection, and secondarily on complication rates. However, outcomes are best reflected by the delicate balance of efficacy and complications at patient level.

Objective

This study proposes a novel way to classify and report outcomes, integrating efficacy and safety at the patient level.

Methods

Retrospective chart review of all pure endoscopic transsphenoidal surgical procedures for acromegaly, Cushing's disease, and prolactinoma between 2010 and 2018 in a single tertiary referral center. We present our results in a classic (remission and

SUBMITTER: de Vries F 

PROVIDER: S-EPMC8372644 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature