The Role of Thyroid in Renovascular Function: Independent Association of Serum TSH With Renal Plasma Flow.

ABSTRACT:

Context

There are well-established interactions between the thyroid and the kidney. Thyroid hypofunction is associated with reduced renal plasma flow (RPF), and hypothyroidism is highly prevalent in chronic kidney disease; however, less is known about the thyroid-kidney axis in the euthyroid state.

Objective

This work aimed to study the association of thyroid function with renovascular parameters in a well-phenotyped cohort of euthyroid normotensive and hypertensive individuals.

Methods

This cross-sectional, multicenter study of the HyperPATH Consortium took place in 5 US and European academic institutions. A total of 789 individuals, aged 18 to 65 years, with serum thyrotropin (TSH) 0.4 to 5.5 mIU/L, participated; individuals with uncontrolled or secondary hypertensi

SUBMITTER: Pappa T 

PROVIDER: S-EPMC8372660 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature