Enrollment, retention, and strategies for including disadvantaged populations in randomized controlled trials: a systematic review protocol.

ABSTRACT:

Background

Many randomized controlled trials fail to reach their target sample size. When coupled with the omission and underrepresentation of disadvantaged groups in randomized controlled trials, many trials fail to obtain data that accurately represents the true diversity of their target population. Policies and practices have been implemented to increase representation of disadvantaged groups in many randomized controlled trials, with some trials specifically targeting such groups. To our knowledge, no systematic review has quantified the enrollment metrics and effectiveness of inclusion and retention strategies in randomized controlled trials focused on disadvantaged populations specifically.

Methods

We will conduct a systematic search across EMBASE, MEDLINE, Web of Scie

SUBMITTER: LaPlante A 

PROVIDER: S-EPMC8372683 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature