Eyeglasses-based tear biosensing system: Non-invasive detection of alcohol, vitamins and glucose.

ABSTRACT: We report on a wearable tear bioelectronic platform, integrating a microfluidic electrochemical detector into an eyeglasses nose-bridge pad, for non-invasive monitoring of key tear biomarkers. The alcohol-oxidase (AOx) biosensing fluidic system allowed real-time tear collection and direct alcohol measurements in stimulated tears, leading to the first wearable platform for tear alcohol monitoring. Placed outside the eye region this fully wearable tear-sensing platform addresses drawbacks of sensor systems involving direct contact with the eye as the contact lenses platform. Integrating the wireless electronic circuitry into the eyeglasses frame thus yielded a fully portable, convenient-to-use fashionable sensing device. The tear alcohol sensing concept was demonstrated for monitoring of alc

SUBMITTER: Sempionatto JR 

PROVIDER: S-EPMC8372769 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature