Childhood neurodevelopmental markers and risk of premature mortality: Follow-up to age 60-65 years in the Aberdeen Children of the 1950s study.

ABSTRACT:

Background

Individual neurodevelopmental disorders are associated with premature mortality. Little is known about the association between multiple neurodevelopmental markers and premature mortality at a population level. The ESSENCE (Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations) approach considers multiple neurodevelopmental parameters, assessing several markers in parallel that cluster, rather than considering individual diagnostic categories in isolation.

Objectives

To determine whether childhood neurodevelopmental markers, including reduced intellectual functioning, are associated with all-cause premature mortality.

Methods and procedures

In a general population cohort study (n = 12,150) with longitudinal follow up from childhood t

SUBMITTER: Warrilow A 

PROVIDER: S-EPMC8372930 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature