Epidemiology and Antifungal Susceptibilities of Mucoralean Fungi in Clinical Samples from the United States.

ABSTRACT: The global incidence of mucormycosis has increased in recent years owing to higher numbers of individuals at risk for these infections. The diagnosis and treatment of this aggressive fungal infection are of clinical concern due to differences in species distribution in different geographic areas and susceptibility profiles between different species that are capable of causing highly aggressive infections. The purpose of this study was to evaluate the epidemiology and susceptibility profiles of Mucorales isolates in the United States over a 52-month period. Species identification was performed by combined phenotypic characteristics and DNA sequence analysis, and antifungal susceptibility testing was performed by CLSI M38 broth microdilution for amphotericin B, isavuconazole, itraconazole, a

SUBMITTER: Badali H 

PROVIDER: S-EPMC8373021 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature