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Male microchimerism in females: a quantitative study of twin pedigrees to investigate mechanisms.


ABSTRACT:

SUBMITTER: Johnson BN 

PROVIDER: S-EPMC8373473 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature

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Male microchimerism in females: a quantitative study of twin pedigrees to investigate mechanisms.

Johnson B N BN   Peters H E HE   Lambalk C B CB   Dolan C V CV   Willemsen G G   Ligthart L L   Mijatovic V V   Hottenga J J JJ   Ehli E A EA   Boomsma D I DI  

Human reproduction (Oxford, England) 20210801 9


<h4>Study question</h4>Does having a male co-twin, older brothers, or sons lead to an increased probability of persistent male microchimerism in female members of twin pedigrees?<h4>Summary answer</h4>The presence of a male co-twin did not increase risk of male microchimerism and the prevalence of male microchimerism was not explained by having male offspring or by having an older brother.<h4>What is known already</h4>Microchimerism describes the presence of cells within an organism that origina  ...[more]

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