Ambient fine particulate matter exposure and incident mild cognitive impairment and dementia.

ABSTRACT:

Background/objective

Poor air quality is implicated as a risk factor for cognitive impairment and dementia. Few studies have examined these associations longitudinally in well-characterized population-based cohorts with standardized annual assessment of both mild cognitive impairment (MCI) and dementia. We investigated the association between estimated ambient fine particulate matter (PM_2.5 ) and risk of incident MCI and dementia in a post-industrial region known for historically poor air quality.

Setting/participants

Adults aged 65+ years in a population-based cohort (n = 1572).

Measurements

Census tract level PM_2.5 from Environmental Protection Agency (EPA) air quality monitors; Clinical Dementia Rating (CDR)®.

Design

We estimated ambien

SUBMITTER: Sullivan KJ 

PROVIDER: S-EPMC8373708 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature