Restricted mean survival time versus conventional measures for treatment decision-making.

ABSTRACT:

Background/objectives

Restricted mean survival time (RMST) summarizes treatment effect in terms of a gain or loss in the event-free days. It remains uncertain whether communicating treatment benefit and harm using RMST-based summary is more effective than conventional summary based on absolute and relative risk reduction. We compared the effect of RMST-based approach and conventional approach on decisional conflict using an example of intensive versus standard blood pressure-lowering strategies.

Design

On-line survey.

Setting

A convenience sample of patients in the United States.

Participants

Two hundred adults aged 65 and older with hypertension requiring anti-hypertensive treatment (response rate 85.5%).

Interventions

Participants were randomly assigne

SUBMITTER: Kim DH 

PROVIDER: S-EPMC8373742 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature