Correlations Between the Adenotonsillar Microbiome and Clinical Characteristics of Pediatric Patients With Snoring.

ABSTRACT:

Objectives

Few studies have reported combined analyses of the microbiome of the adenoids and tonsils in pediatric patients with snoring, and correlations of the adenotonsillar microbiome with clinical characteristics have not been evaluated to date. The aim of this study was to characterize the adenotonsillar microbiome and to determine its correlations with the subjective symptoms of pediatric patients with snoring and with levels of regional mucosal immune molecules.

Methods

Twenty-four children who underwent tonsillectomy with adenoidectomy owing to snoring were enrolled in this cross-sectional study conducted between August 2017 and December 2018. The microbiome of the adenoids and tonsils was characterized, and its alpha- and beta-diversity was determined. Clinical char

SUBMITTER: Kim KS 

PROVIDER: S-EPMC8373842 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature