Effects of Smoking Status and State on Intrinsic Connectivity.

ABSTRACT:

Background

Smoking behavior during the first 24 hours of a quit attempt is a significant predictor of longer-term abstinence, yet little is known about the neurobiology of early tobacco abstinence. Specifically, the effects of acute tobacco deprivation and reinstatement on brain function-particularly at the level of large-scale network dynamics and assessed across the entire brain-remain incompletely understood. To address this gap, this study used a mixed within- and between-subjects design to assess the effects of smoking status (yes/no smoker) and state (deprived vs. satiated) on whole-brain patterns of intrinsic connectivity.

Methods

Participants included 42 tobacco smokers who underwent resting-state functional magnetic resonance imaging following overnight abstinence (

SUBMITTER: Yip SW 

PROVIDER: S-EPMC8373998 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature