A rapid analysis of Bisphenol A using MISPE coupled with HPLC-FLD in tissues of food-producing animals.

ABSTRACT: Bisphenol A (BPA) is a highly-produced organic compound of anthropogenic origin with a wide-range use and is ubiquitously present in both living organisms and the environment. A previously published analytical method for testing of the free (aglycone) BPA in foodstuffs was simplified and optimized for sheep muscle tissue, kidney and liver, by using only a single MISPE purification step allied with HPLC-FLD analysis. The recovery rates and RSD values over a concentration range of 1-10 µg/kg were in the range of 67‒86% and 3‒34%, respectively, while linearity in the matrix, represented by the r², was ≥0.999. LOD values were 0.5‒1 µg/kg and LOQ values were 1 µg/kg. The analytical method used is a contribution to the field of veterinary toxicology and food testing and also proved to

SUBMITTER: Cerkvenik-Flajs V 

PROVIDER: S-EPMC8374360 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature