Association of Statin Treatment With Progression of Coronary Atherosclerotic Plaque Composition.

ABSTRACT:

Importance

The density of atherosclerotic plaque forms the basis for categorizing calcified and noncalcified morphology of plaques.

Objective

To assess whether alterations in plaque across a range of density measurements provide a more detailed understanding of atherosclerotic disease progression.

Design, setting, and participants

This cohort study enrolled 857 patients who underwent serial coronary computed tomography angiography 2 or more years apart and had quantitative measurements of coronary plaques throughout the entire coronary artery tree. The study was conducted from 2013 to 2016 at 13 sites in 7 countries.

Main outcomes and measures

The main outcome was progression of plaque composition of individual coronary plaques. Six plaque composition types wer

SUBMITTER: van Rosendael AR 

PROVIDER: S-EPMC8374741 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature