Monitoring of circulating epithelial tumor cells using the Maintrac^® method and its potential benefit for the treatment of patients with colorectal cancer.

ABSTRACT: Circulating tumor cells are an important link between primary tumors and metastases. A longitudinal monitoring of their numbers and properties can provide valuable information on therapy response and disease progression for patients with colorectal cancer. As several techniques for the detection of circulating tumor cells are notorious for yielding low detection rates in patients with non-metastatic colorectal cancer, the present study aimed to perform a proof-of-principle study using the Maintrac^® approach for an assessment of circulating epithelial tumor cells (CETCs) in patients with colorectal cancer receiving neoadjuvant and/or adjuvant radio/chemotherapy (R/CT). CETCs in the peripheral blood of 22 patients with colorectal cancer were quantified by fluorescence image analys

SUBMITTER: Gold M 

PROVIDER: S-EPMC8375047 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature