Searchlight: automated bulk RNA-seq exploration and visualisation using dynamically generated R scripts.

ABSTRACT:

Background

Once bulk RNA-seq data has been processed, i.e. aligned and then expression and differential tables generated, there remains the essential process where the biology is explored, visualized and interpreted. Without the use of a visualisation and interpretation pipeline this step can be time consuming and laborious, and is often completed using R. Though commercial visualisation and interpretation pipelines are comprehensive, freely available pipelines are currently more limited.

Results

Here we demonstrate Searchlight, a freely available bulk RNA-seq visualisation and interpretation pipeline. Searchlight provides: a comprehensive statistical and visual analysis, focusing on the global, pathway and single gene levels; compatibility with most differential experimenta

SUBMITTER: Cole JJ 

PROVIDER: S-EPMC8375142 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature