Neurally driven synthesis of learned, complex vocalizations.

ABSTRACT: Brain machine interfaces (BMIs) hold promise to restore impaired motor function and serve as powerful tools to study learned motor skill. While limb-based motor prosthetic systems have leveraged nonhuman primates as an important animal model,^1-4 speech prostheses lack a similar animal model and are more limited in terms of neural interface technology, brain coverage, and behavioral study design.^5-7 Songbirds are an attractive model for learned complex vocal behavior. Birdsong shares a number of unique similarities with human speech,^8-10 and its study has yielded general insight into multiple mechanisms and circuits behind learning, execution, and maintenance of vocal motor skill.^11-18 In addition, the biomechanics of song production bear similari

SUBMITTER: Arneodo EM 

PROVIDER: S-EPMC8375361 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature