COVID-19 vaccine strategies for Aotearoa New Zealand: a mathematical modelling study.

ABSTRACT: Background: COVID-19 elimination measures, including border closures have been applied in New Zealand. We have modelled the potential effect of vaccination programmes for opening borders. Methods: We used a deterministic age-stratified Susceptible, Exposed, Infectious, Recovered (SEIR) model. We minimised spread by varying the age-stratified vaccine allocation to find the minimum herd immunity requirements (the effective reproduction number R_eff<1 with closed borders) under various vaccine effectiveness (VE) scenarios and R₀ values. We ran two-year open-border simulations for two vaccine strategies: minimising R_eff and targeting high-risk groups. Findings: Targeting of high-risk groups will result in lower hospitalisations and deaths in

SUBMITTER: Nguyen T 

PROVIDER: S-EPMC8375363 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature