Safe balloon inflation parameters for resuscitative endovascular balloon occlusion of the aorta.

ABSTRACT:

Background

Noncompressible hemorrhage is a leading cause of preventable death in civilian and military trauma populations. Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a promising method for controlling noncompressible hemorrhage, but safe balloon inflation parameters are not well defined. Our goal was to determine the balloon inflation parameters associated with benchtop flow occlusion and aortic/balloon rupture in ex vivo human aortas and test the hypothesis that optimal balloon inflation characteristics depend on systolic pressure and subject demographics.

Methods

Aortic occlusion parameters in human thoracic aortas (TAs) and abdominal aortas (AAs) from 79 tissue donors (median ± SD age, 52 ± 18 years [range, 13-75 years]; male, 52; female, 27) wer

SUBMITTER: Maleckis K 

PROVIDER: S-EPMC8375400 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature