Short versus standard peroral endoscopic myotomy for esophageal achalasia: a systematic review and meta-analysis.

ABSTRACT:

Background

Peroral endoscopic myotomy (POEM) is increasingly used to treat esophageal achalasia, but is associated with a high rate of gastroesophageal reflux disease (GERD). The aim of our meta-analysis was to compare short and standard POEM in terms of clinical success and postoperative GERD.

Methods

We conducted a systematic review and meta-analysis of studies that compared POEM using short myotomy with standard myotomy. The primary outcome was clinical success. Secondary outcomes were postoperative GERD, perioperative complications, operation time, and length of hospital stay. A random-effects model was used to calculate the risk ratios (RR), mean differences (MD), and confidence intervals (CI). A P-value <0.05 was considered statistically significant.

Results

We

SUBMITTER: Ghazaleh S 

PROVIDER: S-EPMC8375650 | biostudies-literature | 2021 Sep-Oct

REPOSITORIES: biostudies-literature