Prospective Evaluation of Repeatability and Robustness of Radiomic Descriptors in Healthy Brain Tissue Regions In Vivo Across Systematic Variations in T2-Weighted Magnetic Resonance Imaging Acquisition Parameters.

ABSTRACT:

Background

Radiomic descriptors from magnetic resonance imaging (MRI) are promising for disease diagnosis and characterization but may be sensitive to differences in imaging parameters.

Objective

To evaluate the repeatability and robustness of radiomic descriptors within healthy brain tissue regions on prospectively acquired MRI scans; in a test-retest setting, under controlled systematic variations of MRI acquisition parameters, and after postprocessing.

Study type

Prospective.

Subjects

Fifteen healthy participants.

Field strength/sequence

A 3.0 T, axial T₂ -weighted 2D turbo spin-echo pulse sequence, 181 scans acquired (2 test/retest reference scans and 12 with systematic variations in contrast weighting, resolution, and acceleration per par

SUBMITTER: Eck B 

PROVIDER: S-EPMC8376104 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature