Vital sign metrics of VLBW infants in three NICUs: implications for predictive algorithms.

ABSTRACT:

Background

Continuous heart rate (HR) and oxygenation (SpO₂) metrics can be useful for predicting adverse events in very low birth weight (VLBW) infants. To optimize the utility of these tools, inter-site variability must be taken into account.

Methods

For VLBW infants at three neonatal intensive care units (NICUs), we analyzed the mean, standard deviation, skewness, kurtosis, and cross-correlation of electrocardiogram HR, pulse oximeter pulse rate, and SpO₂. The number and durations of bradycardia and desaturation events were also measured. Twenty-two metrics were calculated hourly, and mean daily values were compared between sites.

Results

We analyzed data from 1168 VLBW infants from birth through day 42 (35,238 infant-days). HR and SpO_2</

SUBMITTER: Zimmet AM 

PROVIDER: S-EPMC8376742 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature