Anisotropic Mechanical Properties of the Human Uterus Measured by Spherical Indentation.

ABSTRACT: The mechanical function of the uterus is critical for a successful pregnancy. During gestation, uterine tissue grows and stretches to many times its size to accommodate the growing fetus, and it is hypothesized the magnitude of uterine tissue stretch triggers the onset of contractions. To establish rigorous mechanical testing protocols for the human uterus in hopes of predicting tissue stretch during pregnancy, this study measures the anisotropic mechanical properties of the human uterus using optical coherence tomography (OCT), instrumented spherical indentation, and video extensometry. In this work, we perform spherical indentation and digital image correlation to obtain the tissue's force and deformation response to a ramp-hold loading regimen. We translate previously reported fiber arc

SUBMITTER: Fang S 

PROVIDER: S-EPMC8376808 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature