Paternal prescription medication before conception: A retrospective cohort study of all births in Denmark 1997-2017.

ABSTRACT:

Aim

To study what medication fathers are being prescribed in the months preceding conception.

Methods

A retrospective cohort study of Danish national registries, comprising all births in Denmark 1997-2017 (1.3 million births). Time trends and absolute levels of paternal prescription medication in the 6 months prior to conception were assessed. While all medications were examined (N = 1335), we focused on the main medication groups, medications that have increased in use over time, and medications for which previous evidence exists of an effect on sperm quality.

Results

The average number of prescriptions increased over the study period (from 0.75 prescriptions to 0.82 per birth). Polypharmacy (three or more prescriptions) increased from less than 8% to 10% of f

SUBMITTER: Wensink MJ 

PROVIDER: S-EPMC8377090 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature