Ameliorative effect of Annona reticulata L. leaf extract on antihyperglycemic activity and its hepato-renal protective potential in streptozotocin induced diabetic rats.

ABSTRACT:

Background

Annona reticulata L. is a traditionally important plant due to its versatile source of medicine and industrial products. It is used to treat cardiac problems, wound healing, diabetes, ulcers and bacterial infections. As it is a commercial fruit bearing plant, wide range studies on this plant reaches the mankind efficiently.

Objective(s)

The present study was focussed on antihyperglycemic potential of A. reticulata leaves under in vitro and in vivo.

Material and methods

The in vitro phytochemical analysis, total phenolic, flavonoid content, inhibition activity on alpha amylase and alpha glucosidase enzymes were determined for various solvent extracts, followed by in vivo oral toxicity, short term, dose dependant antihyperglycemic studies, oral glucose tolera

SUBMITTER: Pulivarthi V 

PROVIDER: S-EPMC8377183 | biostudies-literature | 2021 Jul-Sep

REPOSITORIES: biostudies-literature