Association of Multifocality With Prognosis of Papillary Thyroid Carcinoma: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

Multifocality is common in papillary thyroid carcinoma (PTC), but it is unclear whether multifocal tumors are associated with tumor recurrence or cancer-specific survival.

Objective

To compare tumor recurrence rates in patients with multifocal vs unifocal PTCs.

Data sources

We searched PubMed, SCOPUS, Web of Science Core Collection, and Cochrane Database of Systematic Reviews for pertinent studies published in English from inception to June 30, 2020.

Study selection

The search strategy yielded 26 studies that compared tumor recurrence in patients with multifocal vs unifocal PTC.

Data extraction and synthesis

Data was extracted in accordance with the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-analyses guide

SUBMITTER: Kim H 

PROVIDER: S-EPMC8377609 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature