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Transcriptomic Analysis of Salivary Glands of Ornithodoros brasiliensis Aragao, 1923, the Agent of a Neotropical Tick-Toxicosis Syndrome in Humans.


ABSTRACT: Tick salivary glands produce and secrete a variety of compounds that modulate host responses and ensure a successful blood meal. Despite great progress made in the identification of ticks salivary compounds in recent years, there is still a paucity of information concerning salivary molecules of Neotropical argasid ticks. Among this group of ticks, considering the number of human cases of parasitism, including severe syndromes and hospitalization, Ornithodoros brasiliensis can be considered one of the major Neotropical argasid species with impact in public health. Here, we describe the transcriptome analysis of O. brasiliensis salivary glands (ObSG). The transcriptome yielded ~14,957 putative contigs. A total of 368 contigs were attributed to secreted proteins (SP), which rep

SUBMITTER: Reck J 

PROVIDER: S-EPMC8378177 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature