Understanding the immunological aspects of SARS-CoV-2 causing COVID-19 pandemic: A therapeutic approach.

ABSTRACT: In December 2019, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), a novel variant of coronavirus has emerged from Wuhan in China and has created havoc impulses across the world with a larger number of fatalities. At the same time, studies are on roll to discover potent vaccine against it or repurposing of approved drugs which are widely adopted are under trial to eradicate the SARS-CoV-2 causing COVID-19 pandemic. Reports have also shown that there are asymptomatic carriers of COVID-19 disease who can transmit the disease to others too. However, the first line defense of the viral attack is body's strong and well-coordinated immune response producing excessive inflammatory innate reaction, thus impaired adaptive host immune defense which lead to death upon the malfunctioning.

SUBMITTER: Das A 

PROVIDER: S-EPMC8378842 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature