Fatigue following mild traumatic brain injury relates to visual processing and effort perception in the context of motor performance.

ABSTRACT:

Introduction

Following mild traumatic brain injury (mTBI), a substantial number of patients experience disabling fatigue for months after the initial injury. To date, the underlying mechanisms of fatigue remain unclear. Recently, it was shown that mTBI patients with persistent fatigue do not demonstrate increased performance fatigability (i.e., objective performance decline) during a sustained motor task. However, it is not known whether the neural activation required to sustain this performance is altered after mTBI.

Methods

Blood oxygen level-dependent (BOLD) fMRI data were acquired from 19 mTBI patients (>3 months post-injury) and 19 control participants during two motor tasks. Force was recorded from the index finger abductors of both hands during submaximal contractions

SUBMITTER: Prak RF 

PROVIDER: S-EPMC8379650 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature