Comparison of 16S and whole genome dog microbiomes using machine learning.

ABSTRACT:

Background

Recent advances in sequencing technologies have driven studies identifying the microbiome as a key regulator of overall health and disease in the host. Both 16S amplicon and whole genome shotgun sequencing technologies are currently being used to investigate this relationship, however, the choice of sequencing technology often depends on the nature and experimental design of the study. In principle, the outputs rendered by analysis pipelines are heavily influenced by the data used as input; it is then important to consider that the genomic features produced by different sequencing technologies may emphasize different results.

Results

In this work, we use public 16S amplicon and whole genome shotgun sequencing (WGS) data from the same dogs to investigate the relati

SUBMITTER: Lewis S 

PROVIDER: S-EPMC8379800 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature