Simethicone administration improves gastric cleanness for esophagogastroduodenoscopy: a randomized clinical trial.

ABSTRACT:

Background

Esophagogastroduodenoscopy is very useful in diagnosing and treating upper gastrointestinal mucosal disorders, but too much foam and water in stomach decrease its diagnostic efficiency. Simethicone administration can help remove excessive foam.

Aims

To determine the optimal simethicone administration strategies in a comparative randomized controlled clinical trial.

Methods

Adult outpatients with indications for esophagogastroduodenoscopy were enrolled and randomly divided into group 1 (simethicone solution intake 20-30 min before procedure, n = 110), group 2 (simethicone solution intake 31-60 min before procedure, n = 92), and group 3 (simethicone solution intake > 60 min before procedure). Primary and secondary outcomes were procedure time and the patients

SUBMITTER: Sun X 

PROVIDER: S-EPMC8379843 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature