Ontology highlight
ABSTRACT:
SUBMITTER: Zolty R
PROVIDER: S-EPMC8380049 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Journal of experimental pharmacology 20210817
Pulmonary arterial hypertension (PAH) is a progressive and devastating disease characterized by pulmonary artery vasoconstriction and vascular remodeling leading to vascular rarefaction with elevation of pulmonary arterial pressures and pulmonary vascular resistance. Often PAH will cause death from right heart failure. Current PAH-targeted therapies improve functional capacity, pulmonary hemodynamics and reduce hospitalization. Nevertheless, today PAH still remains incurable and is often refract ...[more]