[¹⁸F]FDG-PET/CT in prone compared to supine position for optimal axillary staging and treatment in clinically node-positive breast cancer patients with neoadjuvant systemic therapy.

ABSTRACT:

Purpose

Axillary staging before neoadjuvant systemic therapy in clinically node-positive breast cancer patients with tailored axillary treatment according to the Marking Axillary lymph nodes with radioactive iodine seeds (MARI)-protocol, a protocol developed at the Netherlands Cancer Institute, is performed with [¹⁸F] fluorodeoxyglucose (FDG) positron emission tomography and computed tomography (PET/CT). We aimed to assess the value of FDG-PET/CT in prone compared to standard supine position for axillary staging.

Methods

We selected patients with FDG-PET/CT in supine and prone position who underwent the MARI-protocol. One hour after administration of 3.5 MBq/kg, [¹⁸F]FDG-PET was performed with a low-dose prone position CT-thorax followed by a supine who

SUBMITTER: van Loevezijn AA 

PROVIDER: S-EPMC8380204 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature