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Emerging treatment modalities for systemic therapy in hepatocellular carcinoma.


ABSTRACT: Hepatocellular carcinoma (HCC) has long been a major global clinical problem as one of the most common malignant tumours with a high rate of recurrence and mortality. Although potentially curative therapies are available for the early and intermediate stages, the treatment of patients with advanced HCC remains to be resolved. Fortunately, the past few years have shown the emergence of successful systemic therapies to treat HCC. At the molecular level, HCC is a heterogeneous disease, and current research on the molecular characteristics of HCC has revealed numerous therapeutic targets. Targeted agents based on signalling molecules have been successfully supported in clinical trials, and molecular targeted therapy has already become a milestone for disease management in patients with HCC. Im

SUBMITTER: Qing X 

PROVIDER: S-EPMC8380325 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature