When an obscurity becomes trend: social-media descriptions of tianeptine use and associated atypical drug use.

ABSTRACT: Background: Originally believed to be an atypical antidepressant acting at serotonin transporters, tianeptine is now known to also be an atypical agonist at mu-opioid receptors. Its nonmedical use may be increasing amidst the broader context of novel drug and supplement use.Objectives: To analyze social-media text from current, former, and prospective tianeptine users for better understanding of their conceptualizations of tianeptine, motives for and patterns of use, and reported benefits and harms.Methods: Reddit posts were obtained and thematically coded; additional quantitative analyses were conducted.Results: A total of 210 posts mentioning tianeptine were made between 2012 and 2020. Eighteen thematic categories were identified, 10 of which were consistent w

SUBMITTER: Smith KE 

PROVIDER: S-EPMC8380661 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature